San Francisco 49ers @ San Diego Chargers (-10)
Chargers are in must win mode, and rarely do they lose in December. Phillip Rivers is money in the bank and the fact that Frank Gore isn't even in the picture tonight is a huge disadvantage for the 49ers offense. Alex Smith will be back to his old form. Don't be surprised by another shutout by the Chargers defense.
PICK: SAN DIEGO CHARGERS 27 - San Francisco 49ers 3